Straightforward synthesis of cytosporone analogs AMS35AA and AMS35BB

Cytosporones, a class of octaketide resorcinolic lipids, have drawn the attention researchers for exhibiting number notable biological properties. Herein, we describe routes to synthesize bioactive synthetic lipids AMS35AA and AMS35BB with excellent overall yields using 3,5-dimethoxybenzoic acid as starting material. The methods proved remarkably efficient achieve target compounds comprise synthesis catalyzed by ascorbic (vitamin C).